Molecular Basis of Cancer, 4th ed.

本書の特色

癌を分子生物学に捉えようとする本書は，悪性腫瘍の発生機序・病理とその処置を根本的なところから教えてくれる．科学的根拠に基づく癌発生の理解に基づく適切な治療方法の策定，多数のカラー挿図を伴った見やすいフォーマットによる病態理解の容易化，病理から治療にいたる過程の論理的把握によるクリティカルな情報の速やかな発見，の三つを柱としている．Expert Consultが付属している．

Table of Contents
Part I: Carcinogenesis and Cancer Genetics
1. Cancer, A Genetic Disorder
2. Oncogenes and Signal Transduction
3. Tumor Suppressor Genes
4. Genomic Instability and DNA Repair
5. Epigenetics and Cancer
6. Infectious Agents and Cancer
7. Environmental Carcinogenesis
8. Animal Models: Flies, Fish and Yeast
9. Genetic Mouse Models of Cancer
Part II: Cancer Biology
10. Cancer Stem Cells
11. Regulation of the Cell Cycle
12. Cell Growth
13. Cancer Cell Metabolism
14. Apoptosis, Autophagy and Necrosis
15. Cell Growth Arrest and Senescence
16. Stromal-Cancer Interactions in the Microenvironment
17. Hypoxia and Angiogenesis
18. Invasion and Metastasis
19. Inflammation and Cancer
20. Molecular Pathways and Systems Biology
Part III: Molecular Pathology and Diagnostics
21. Biomarkers Assessing Risk of Cancer
22. Biomarkers for Detecting Cancer: Molecular Screening
23. Biomarkers for Predicting Response to Specific Therapy
24. The Technology of Analyzing Nucleic Acids
25. Imaging Cancerv